Butrim: A Brand of Sulfamethoxazole + Trimethoprim (Co-trimoxazole)

What it is

Butrim is a brand of sulfamethoxazole + trimethoprim, a combination antibiotic that belongs to the sulfonamide class. It works by stopping the growth of certain bacteria.

What it's used for

Butrim is used to treat bacterial infections that are proven or strongly suspected to be caused by susceptible bacteria. Common uses include urinary tract infections, shigellosis (a type of diarrheal infection), and acute otitis media (middle ear infection) in children. Using it only when necessary helps reduce the development of drug-resistant bacteria.

How it's taken

Butrim tablets are taken by mouth. The dose and duration depend on the infection, the patient's age, and weight. For example, in adults with urinary tract infections, the typical dose is two tablets every 12 hours for 10 to 14 days. For children, the dose is calculated based on weight. Butrim is not recommended for children under 2 months of age. Always follow your doctor or pharmacist's instructions exactly.

Common side effects

The most common side effects are stomach upset (nausea, vomiting, loss of appetite) and allergic skin reactions such as rash or hives. Serious but rare side effects can occur, including severe skin reactions (Stevens-Johnson syndrome), blood disorders, and liver damage. Seek medical attention if you notice unusual bruising, bleeding, fever, or a severe rash.

Important cautions

Do not use Butrim if you are allergic to sulfonamides or trimethoprim, have a history of low platelets caused by these medicines, have megaloblastic anemia from folate deficiency, or have severe liver disease. It should not be given to infants under 2 months old. If you are pregnant or planning to become pregnant, talk to your doctor because some studies suggest an increased risk of birth defects. Always tell your doctor about all other medicines you take.

Frequently asked questions