Betaclav (Amoxicillin + Clavulanic Acid) Overview

What it is

Betaclav is a brand of the generic combination amoxicillin + clavulanic acid. It is an antibiotic that contains amoxicillin, a penicillin-type antibiotic, and clavulanic acid, a beta-lactamase inhibitor that helps the amoxicillin work against certain resistant bacteria. It belongs to a class of drugs known as beta-lactam antibiotics with a beta-lactamase inhibitor.

What it's used for

Betaclav is used to treat infections in adults and children caused by susceptible bacteria. These include lower respiratory tract infections (such as pneumonia), acute bacterial otitis media (ear infections), sinusitis, and skin and skin structure infections. It works against bacteria like Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, and Escherichia coli that produce an enzyme called beta-lactamase.

How it's taken

Betaclav comes as a tablet containing 500 mg of amoxicillin and 125 mg of clavulanic acid. It is taken by mouth. The dose depends on the type and severity of the infection, the patient's weight, and kidney function. Typical adult doses are based on the amoxicillin component: 500 mg or 875 mg every 12 hours, or 250 mg or 500 mg every 8 hours. For children, doses are based on weight and given every 12 or 8 hours. Always follow the prescription of your doctor or pharmacist. Do not change your dose without medical advice.

Common side effects

The most common side effects reported with Betaclav include diarrhoea or loose stools (9%), nausea (3%), skin rashes or hives (3%), vomiting (1%), and vaginal yeast infection (1%). Serious side effects can occur, such as severe allergic reactions (anaphylaxis), severe skin reactions, liver problems (including jaundice), and diarrhoea caused by Clostridioides difficile. If you experience signs of an allergic reaction, severe skin rash, yellowing of the skin or eyes, or persistent diarrhoea, seek medical help immediately.

Important cautions

Do not use Betaclav if you have a history of serious allergic reaction to amoxicillin, clavulanate, or other beta‑lactam antibiotics (such as penicillins or cephalosporins). Also do not use if you have had liver problems or cholestatic jaundice after taking amoxicillin/clavulanate in the past. If you have mononucleosis, avoid this medicine because it can cause a skin rash. Use with caution if you have kidney disease; your doctor may need to adjust the dose. Stop taking Betaclav and contact your doctor if you develop signs of liver inflammation (e.g., abdominal pain, dark urine, yellowing of the eyes).

Frequently asked questions