Amclavin 312.5 for Oral: A Brand of Amoxicillin and Clavulanic Acid

What it is

Amclavin 312.5 for Oral is a brand of the generic combination amoxicillin and clavulanic acid. It is an antibiotic that belongs to the penicillin class with a beta-lactamase inhibitor. The clavulanic acid helps stop bacteria from breaking down amoxicillin, making the antibiotic more effective against certain resistant bacteria.

What it's used for

Amclavin is indicated for the treatment of infections caused by susceptible bacteria, including lower respiratory tract infections (such as bronchitis), acute bacterial ear infections (otitis media), sinusitis, and skin and soft tissue infections. It is specifically effective against bacteria that produce beta-lactamase enzymes, such as certain strains of Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus.

How it's taken

Amclavin 312.5 for Oral is taken by mouth after the powder is mixed with water to form a suspension. The dose is typically based on the amoxicillin component and depends on the patient's body weight, age, and the severity of the infection. For adults and children over 40 kg, it is usually given every 8 or 12 hours. For younger children, the dose is calculated as milligrams per kilogram of body weight per day, divided into two or three doses. Always follow your doctor or pharmacist’s instructions exactly; do not change your dose without medical advice.

Common side effects

The most common side effects reported with Amclavin include diarrhoea or loose stools (9%), nausea (3%), skin rash or hives (3%), vomiting (1%), and vaginal yeast infection (1%). Most of these effects are mild and go away on their own, but you should inform your doctor if they persist or become bothersome. Serious side effects are rare but can include severe allergic reactions, liver problems, and severe diarrhoea due to Clostridioides difficile infection.

Important cautions

Amclavin should not be used if you have a history of a serious allergic reaction to amoxicillin, clavulanate, or any other penicillin or cephalosporin antibiotic. It is also contraindicated if you have ever had liver damage or jaundice caused by this medicine. Use with caution in patients with mononucleosis (a viral infection) because it can cause a widespread rash. If you develop a skin rash, severe diarrhoea, or signs of liver trouble (yellowing of the skin or eyes, dark urine, abdominal pain), stop the medicine and seek medical help immediately. Always tell your doctor about all other medicines you are taking.

Frequently asked questions