Axaclucin 228.5 for Oral: A Brand of Amoxicillin and Clavulanic Acid

What it is

Axaclucin 228.5 for Oral is a brand of amoxicillin and clavulanic acid, a combination antibiotic that belongs to the penicillin group. It is used to treat infections caused by bacteria that may produce an enzyme (beta-lactamase) that can destroy standard penicillins. The clavulanic acid component helps stop this enzyme, allowing amoxicillin to work.

What it's used for

This medicine is indicated for infections in adults and children caused by susceptible bacteria, including: lower respiratory tract infections (e.g., from Haemophilus influenzae or Moraxella catarrhalis), acute middle ear infections (otitis media), sinusitis, and skin and skin structure infections (e.g., from Staphylococcus aureus or Escherichia coli).

How it's taken

Axaclucin 228.5 for Oral is taken by mouth after reconstituting the powder with water as directed. Dosing is typically based on the amoxicillin component and depends on body weight, age, and the type of infection. For patients weighing more than 40 kg (about 88 lbs), common doses are 500 mg or 875 mg every 12 hours, or 250 mg or 500 mg every 8 hours. For children 3 months and older, the dose is usually 25–45 mg/kg/day divided every 12 hours, or 20–40 mg/kg/day divided every 8 hours. Always follow the prescribed dose and complete the full course exactly as advised by a doctor or pharmacist.

Common side effects

The most frequently reported side effects include diarrhoea or loose stools (about 9% of users), nausea (3%), skin rashes and hives (3%), vomiting (1%), and vaginal irritation (1%). If you experience severe or persistent symptoms, contact your healthcare provider.

Important cautions

Axaclucin should not be used in anyone who has had a serious allergic reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to amoxicillin, clavulanate, or other penicillins or cephalosporins. It is also contraindicated in those who have previously developed jaundice or liver problems from amoxicillin and clavulanate. Serious allergic reactions, severe skin reactions, liver dysfunction, and diarrhoea due to Clostridioides difficile (a type of bacteria) have been reported. If you develop a rash, signs of hepatitis, or severe diarrhoea, stop the medicine and seek medical attention. Patients with suspected mononucleosis (glandular fever) should not take this drug because it can cause a widespread rash.

Frequently asked questions