Viridal Duo Continuation Pack 40mcg Powder and solvent for solution for injection (2 Cartridges) - Alprostadil


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Viridal is a medicine containing alprostadil, used in newborns with certain heart defects to temporarily keep a blood vessel open until surgery can be performed.

What it is

Alprostadil is a medicine that belongs to a group called prostaglandins. It is used to temporarily keep the ductus arteriosus (a blood vessel) open in newborn babies who have certain heart defects and depend on this vessel for survival.

What it's used for

Viridal is used as a palliative (temporary) therapy to maintain the patency of the ductus arteriosus in newborns with congenital heart defects such as pulmonary atresia, pulmonary stenosis, tricuspid atresia, tetralogy of Fallot, interruption of the aortic arch, coarctation of the aorta, or transposition of the great vessels. It is given before corrective or palliative surgery.

Common side effects

Common side effects include apnea (temporary stop in breathing) in about 12% of newborns, fever in about 14%, and seizures in about 4%. Other side effects may include flushing, bradycardia, hypotension, diarrhea, and changes in blood sugar levels. Serious side effects include gastric outlet obstruction due to antral hyperplasia with long-term use.

Important cautions

Alprostadil must be diluted before use. Newborns receiving this medicine for more than 120 hours should be monitored for gastric outlet obstruction. There are no known contraindications for this medicine.

Frequently asked questions

What is Viridal (Alprostadil) used for?

It is used as a temporary treatment to keep the ductus arteriosus open in newborns with certain critical heart defects until surgery can be done.

How is Viridal given?

It is given as a continuous infusion into a vein or through an umbilical artery catheter. The dose is based on the baby's weight and is adjusted by a doctor. It must be diluted before use and is given only in a hospital.

What are the common side effects of Alprostadil?

Common side effects include brief pauses in breathing (apnea), fever, and seizures. Flushing, slow heart rate, low blood pressure, and diarrhoea may also occur. Long-term use can cause stomach blockage.

Can I buy Viridal without a prescription in Nigeria?

Yes, this product is classified as over-the-counter (OTC). However, it is used only for newborns in a hospital setting, so a doctor's supervision is required for its use.

Are there any contraindications for Alprostadil?

No, there are no known contraindications for this medicine.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.

Alprostadil is typically given as a continuous infusion into a large vein or through an umbilical artery catheter placed at the ductal opening. The infusion is started at a dose of 0.05 to 0.1 micrograms per kilogram of body weight per minute. It must be diluted before administration. This medicine is given only in a hospital setting by trained healthcare professionals.
Alprostadil must be diluted before use. Newborns receiving this medicine for more than 120 hours should be monitored for gastric outlet obstruction. There are no known contraindications for this medicine.

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