Viridal Duo Continuation Pack 20mcg Powder and solvent for solution for injection (2 Cartridges) - Alprostadil
Alprostadil injection is used in newborn babies with certain heart defects to keep a blood vessel open until surgery can be done. It is given as a continuous infusion by healthcare professionals.
What it is
Alprostadil is a medicine used in newborn infants to temporarily keep open the ductus arteriosus, a blood vessel that normally closes after birth, until corrective or palliative surgery can be performed.
What it's used for
It is used as palliative therapy in neonates with congenital heart defects that depend on a patent ductus arteriosus for survival. These defects include pulmonary atresia, pulmonary stenosis, tricuspid atresia, tetralogy of Fallot, interruption of the aortic arch, coarctation of the aorta, or transposition of the great vessels.
Common side effects
Common side effects include apnea (temporary stopping of breathing) in about 12% of babies, fever in about 14%, flushing in about 10%, and seizures in about 4%. Other reported effects include jitteriness, lethargy, low body temperature, and stiffness.
Important cautions
Alprostadil must be diluted before use. Prolonged use (more than 120 hours) may increase the risk of gastric outlet obstruction due to antral hyperplasia. Apnea can occur, so babies need continuous monitoring. There are no known contraindications.
Frequently asked questions
What is alprostadil injection used for?
It is used in newborn babies with congenital heart defects to temporarily keep the ductus arteriosus open until surgery can be performed.
How is alprostadil given to newborns?
It is given as a continuous infusion into a large vein or through an umbilical artery catheter, always by a healthcare professional.
What are the common side effects of alprostadil?
Common side effects include apnea, fever, flushing, and seizures. Less common effects include jitteriness, lethargy, and hypothermia.
Can I buy alprostadil without a prescription in Nigeria?
Based on available information, this product is classified as over-the-counter. However, alprostadil injection is typically administered in a hospital setting by a doctor.
Is alprostadil safe for all newborns?
Alprostadil has no known contraindications, but it is only used in newborns with specific heart defects and under close medical supervision due to risks like apnea.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
