Silotrif (Silodosin) 8mg capsule is an alpha-blocker medicine used to relieve symptoms of an enlarged prostate (benign prostatic hyperplasia).
What it is
Silodosin is an alpha-1 adrenergic receptor antagonist, a type of medicine known as an alpha-blocker. It works by relaxing the muscles in the prostate and bladder neck to help improve urine flow and reduce symptoms caused by an enlarged prostate.
What it's used for
Silodosin capsules are used to treat the signs and symptoms of benign prostatic hyperplasia (BPH), such as difficulty urinating, weak stream, and frequent urination. It is not used to treat high blood pressure.
Common side effects
Common side effects that may occur in more than 2% of users include retrograde ejaculation (semen goes into the bladder instead of out), dizziness, diarrhoea, a drop in blood pressure when standing up (orthostatic hypotension), headache, nasopharyngitis (common cold), and nasal congestion.
Important cautions
Do not take silodosin if you have severe kidney disease (creatinine clearance less than 30 mL/min), severe liver disease (Child-Pugh score 10 or higher), or if you are taking strong CYP3A4 inhibitors such as ketoconazole, clarithromycin, itraconazole, or ritonavir. Also avoid if you are allergic to silodosin or any ingredient. Be cautious: you may experience dizziness or fainting when standing up, especially when starting treatment. If you have moderate kidney impairment, your doctor may prescribe a lower dose (4 mg). Do not take silodosin with other alpha-blocker medicines. Your doctor should examine you to rule out prostate cancer before starting treatment.
Frequently asked questions
What is silodosin used for?
Silodosin is an alpha-blocker used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), such as difficulty starting urination, weak flow, and frequent urination during the night.
What are the side effects of silodosin?
Common side effects include retrograde ejaculation (semen going into the bladder), dizziness, diarrhoea, headache, stuffy nose, and a drop in blood pressure when standing. If you experience severe dizziness or fainting, contact your doctor.
Can I buy silodosin without a prescription in Nigeria?
Yes, silodosin is available as an over-the-counter (OTC) medicine in Nigeria. You can order it on Drugstore.ng without a prescription.
How should I take silodosin?
Take one 8 mg capsule once daily with a meal. If you have kidney problems, your doctor may recommend a 4 mg dose. Swallow the capsule whole, or if you have difficulty, open it and mix the powder with applesauce—take immediately without chewing.
Who should not take silodosin?
Do not take silodosin if you have severe kidney or liver disease, or if you are taking certain strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin). Also avoid if you are allergic to silodosin or if you are already on other alpha-blockers.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
