Rifampicin 150 mg+ Isoniazid 75 mg + Pyrazinamide 400 mg + Ethambutol 275 mg Tablets USP
This combination tablet contains pyrazinamide and other antituberculosis drugs. It is used for the initial treatment of active tuberculosis in adults and children, always together with other medicines.
What it is
Pyrazinamide is an antituberculosis agent. This fixed-dose combination tablet includes pyrazinamide along with other active ingredients for the treatment of tuberculosis.
What it's used for
This medicine is indicated for the initial treatment of active tuberculosis in adults and children. It must be used in combination with other antituberculosis drugs as part of a complete treatment regimen.
Common side effects
Common side effects include liver problems (hepatotoxicity), nausea, vomiting, loss of appetite, fever, and gout (high uric acid levels causing joint pain). Other rare side effects include blood disorders and skin reactions. If you experience signs of liver damage (yellow skin/eyes, dark urine, stomach pain) or joint pain, contact your doctor immediately.
Important cautions
Do not use this medicine if you have severe liver disease, acute gout, or are allergic to pyrazinamide. Before starting treatment, your doctor may check your liver function and serum uric acid levels. If you have pre-existing liver disease or drink alcohol often, you may need closer monitoring. If signs of liver damage or gouty arthritis appear, treatment should be stopped.
Frequently asked questions
What is pyrazinamide used for?
Pyrazinamide is used for the initial treatment of active tuberculosis, always in combination with other antituberculosis drugs.
What are the side effects of pyrazinamide?
Side effects include liver toxicity, nausea, vomiting, fever, gout, and rarely blood disorders. See a doctor if you have yellow skin or joint pain.
Can I buy pyrazinamide without a prescription in Nigeria?
According to the product information, this medicine is available over the counter. However, it is strongly recommended to use it only under medical supervision for tuberculosis treatment.
How is pyrazinamide taken?
It is taken orally, typically for the first 2 months of a longer tuberculosis regimen. Always follow your doctor's dosing schedule.
What should I avoid while taking pyrazinamide?
Avoid alcohol as it may increase risk of liver damage. Tell your doctor about all other medicines you take.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
