COMBISUNATE DS 80/480 TABS X6
COMBISUNATE is a combination antimalarial tablet containing artemether and lumefantrine. It is used to treat acute, uncomplicated malaria caused by Plasmodium falciparum in adults and children who weigh at least 5 kg and are 2 months or older. This medicine is taken over three days with food and is not for preventing malaria or treating severe malaria.
What it is
COMBISUNATE is a combination medicine that contains two active ingredients: artemether and lumefantrine. It belongs to a class of antimalarial drugs called artemisinin-based combination therapies (ACTs), which work together to kill the malaria parasite in the blood.
What it's used for
This medicine is used to treat acute, uncomplicated malaria infections caused by the Plasmodium falciparum parasite. It is for patients who are 2 months of age or older and weigh at least 5 kilograms. COMBISUNATE is not approved for treating severe or complicated malaria, nor for preventing malaria.
Common side effects
Common side effects in adults include headache, loss of appetite (anorexia), dizziness, weakness (asthenia), and joint pain (arthralgia). Other possible side effects include nausea, vomiting, and abdominal pain. Most side effects are mild and go away on their own. Tell your pharmacist or doctor if any side effect bothers you or does not go away.
Important cautions
Do not use COMBISUNATE if you are allergic to artemether, lumefantrine, or any ingredient in the tablet. Avoid taking this medicine with strong CYP3A4 inducers like rifampin, carbamazepine, phenytoin, or St. John’s wort as they may reduce its effectiveness. Do not take it with other drugs that prolong the heart’s QT interval, and do not use halofantrine within one month of taking COMBISUNATE. This medicine is not for severe malaria or for prevention. Tell your pharmacist about all medicines and herbal products you use.
Frequently asked questions
What is COMBISUNATE used for?
COMBISUNATE is used to treat acute, uncomplicated malaria caused by Plasmodium falciparum. It is not for preventing malaria or for treating severe malaria.
What are the side effects of COMBISUNATE?
Common side effects include headache, loss of appetite, dizziness, weakness, and joint pain. Some people may also experience nausea or vomiting. Most side effects are mild, but talk to your pharmacist if you have concerns.
Can I buy COMBISUNATE without a prescription in Nigeria?
Yes, COMBISUNATE is available over the counter in Nigeria. However, it is still important to use it correctly. Always ask a pharmacist for advice on the right dose and how to take it, especially for children.
How is COMBISUNATE taken?
Take it with food. The usual course is six doses over three days: first dose, second dose 8 hours later, then twice daily (morning and evening) for the next two days. If needed, you can crush the tablet and mix with a little water.
What should I avoid while taking COMBISUNATE?
Avoid taking strong CYP3A4 inducers like rifampin, carbamazepine, phenytoin, or St. John’s wort. Also avoid other antimalarials like halofantrine and any medicines that affect the heart’s rhythm. Always inform your pharmacist of all medicines you are taking.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
