COMBISUNATE 80/480 TAB
COMBISUNATE is a combination antimalarial medicine containing artemether and lumefantrine. It is used to treat acute, uncomplicated malaria caused by Plasmodium falciparum in adults and children weighing at least 5 kg. It is available over the counter in Nigeria.
What it is
COMBISUNATE is a combination antimalarial medicine that contains two active ingredients: artemether and lumefantrine. It belongs to the class of artemisinin-based combination therapies (ACTs) recommended for treating malaria.
What it's used for
It is used to treat acute, uncomplicated malaria infections caused by the parasite Plasmodium falciparum. It is approved for patients aged 2 months and older who weigh at least 5 kg. This medicine is not for severe or complicated malaria, and it should not be used to prevent malaria.
Common side effects
The most common side effects in adults include headache, loss of appetite, dizziness, weakness, joint pain, and muscle pain. Some people may also experience nausea, vomiting, or abdominal pain. These are usually mild and go away on their own.
Important cautions
Do not take COMBISUNATE if you are allergic to artemether or lumefantrine. Avoid use if you have a known heart condition called QT prolongation, low potassium or magnesium levels, or if you are taking other medicines that can affect the heart’s rhythm. Do not take halofantrine (another antimalarial) within one month of taking this medicine. Also, certain drugs such as rifampin, carbamazepine, phenytoin, and St. John’s wort can reduce the effectiveness of COMBISUNATE. Tell your doctor or pharmacist about all medicines you are taking, including herbal products. This medicine is not for severe malaria or for preventing malaria.
Frequently asked questions
What is COMBISUNATE used for?
COMBISUNATE is used to treat acute, uncomplicated malaria caused by Plasmodium falciparum in adults and children weighing at least 5 kg. It is not for severe malaria or for preventing malaria.
What are the side effects of COMBISUNATE?
Common side effects include headache, loss of appetite, dizziness, weakness, joint pain, nausea, and abdominal pain. Serious side effects are rare but may include allergic reactions or heart rhythm changes. Consult a pharmacist or doctor if you have concerns.
Can I buy COMBISUNATE without a prescription in Nigeria?
Yes, COMBISUNATE is an over-the-counter medicine in Nigeria. However, it is still important to use it only for confirmed malaria and to follow the recommended dosage. A pharmacist can advise you on proper use.
How is COMBISUNATE taken?
It is taken orally with food. The usual regimen is 6 doses over 3 days: the first dose, then a second dose after 8 hours, followed by twice-daily doses (morning and evening) for the next 2 days. Always follow the dosage instructions provided by your healthcare provider.
What should I avoid while taking COMBISUNATE?
Avoid taking other antimalarials like halofantrine within one month. Also avoid strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, and St. John's wort, as they can reduce the medicine's effectiveness. Tell your pharmacist about all other medicines you are taking.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
