Coartem 80/480 Tablets (Artemether; Lumefantrine)
Coartem is a fixed-dose combination of artemether and lumefantrine used to treat acute uncomplicated malaria caused by Plasmodium falciparum in adults and children weighing at least 5 kg.
What it is
Coartem is an antimalarial medicine that combines two active ingredients: artemether and lumefantrine. It belongs to a class of drugs called artemisinin-based combination therapies (ACTs).
What it's used for
It is used to treat acute, uncomplicated malaria infections caused by the parasite Plasmodium falciparum. It is for patients aged 2 months and older who weigh at least 5 kg. This medicine works in areas where resistance to older antimalarials like chloroquine has been reported. It is not approved for severe or complicated malaria, nor for preventing malaria.
Common side effects
The most common side effects reported in adults include headache, loss of appetite, dizziness, weakness, and joint pain. Other side effects may occur. If any side effect is severe or does not go away, consult your healthcare provider.
Important cautions
Do not use Coartem if you are allergic to artemether, lumefantrine, or any of its ingredients. Avoid use if you have a heart condition called QT prolongation, low potassium or magnesium levels, or if you are taking other medications that can prolong the QT interval. Coartem may interact with certain drugs, especially strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, and St. John's wort, which can reduce its effectiveness. Also, do not take halofantrine (another antimalarial) within one month of taking Coartem. Always tell your healthcare provider about all medicines you are taking.
Frequently asked questions
What is Coartem used for?
Coartem is used to treat acute, uncomplicated malaria caused by Plasmodium falciparum in patients weighing at least 5 kg and aged 2 months and older.
Can I buy Coartem without a prescription in Nigeria?
Yes, Coartem is available over-the-counter (OTC) in Nigeria. You do not need a prescription to purchase it.
How is Coartem taken?
Coartem tablets are taken by mouth with food. The full course lasts 3 days and includes a total of 6 doses: an initial dose, a second dose after 8 hours, then twice daily (morning and evening) for the next 2 days.
What are the common side effects of Coartem?
Common side effects include headache, loss of appetite, dizziness, weakness, and joint pain. Always consult a healthcare provider if side effects are bothersome.
What should I avoid while taking Coartem?
Avoid taking other antimalarials unless directed by a doctor, and inform your healthcare provider about all medicines you use, especially those affecting heart rhythm or those that are strong CYP3A4 inducers (e.g., rifampin, carbamazepine).
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
