Coartem 20/120 Dispersible Tablets (Artemether; Lumefantrine)


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Coartem is a combination medicine containing artemether and lumefantrine, used to treat acute uncomplicated malaria caused by Plasmodium falciparum in adults and children weighing at least 5 kg. It is effective in areas where chloroquine resistance has been reported and is taken orally with food over 3 days.

What it is

Coartem is an antimalarial medicine that combines two active ingredients — artemether and lumefantrine — to treat infection with the Plasmodium falciparum parasite. It belongs to a class of drugs known as artemisinin-based combination therapies (ACTs).

What it's used for

Coartem is used for the treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients 2 months of age and older with a bodyweight of 5 kg and above. It is not for severe or complicated malaria and is not approved for preventing malaria.

Common side effects

The most common side effects in adults include headache, loss of appetite, dizziness, weakness, and joint pain. Other possible effects include nausea, vomiting, abdominal pain, and sleep disturbances. If any side effect persists or worsens, speak to a healthcare professional.

Important cautions

Do not use Coartem if you are allergic to artemether, lumefantrine, or any of the other ingredients. Avoid co-administration with strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, or St. John’s wort, as they can reduce effectiveness. Coartem should not be used in people with known QT prolongation, low potassium or magnesium levels, or those taking other drugs that prolong the QT interval. Do not take halofantrine within one month of using Coartem. Inform your doctor about all medicines you take, including herbal products.

Frequently asked questions

What is Coartem used for?

Coartem is used to treat acute uncomplicated malaria caused by Plasmodium falciparum in patients weighing at least 5 kg.

What are the common side effects of Coartem?

Common side effects include headache, loss of appetite, dizziness, weakness, and joint pain. Some people may also experience nausea or abdominal discomfort.

Can I buy Coartem without a prescription in Nigeria?

Yes, Coartem is classified as an over-the-counter (OTC) medicine in Nigeria, so you can purchase it without a prescription. However, you should always consult a healthcare professional for proper diagnosis and dosing.

How should Coartem be taken?

Coartem should be taken with food. The tablets can be crushed and mixed with water for easier swallowing. The standard treatment is a 3-day course with 6 doses — an initial dose, a second dose after 8 hours, then twice daily for the next 2 days. Follow the dosing instructions given by your doctor or pharmacist.

Can Coartem be used to prevent malaria?

No, Coartem is not approved for preventing malaria. It is only for treating active malaria infection.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.

Coartem should be taken with food. The tablets may be crushed and mixed with 1 to 2 teaspoons of water just before use, especially for children. The typical course lasts 3 days and includes a total of 6 doses: an initial dose, a second dose 8 hours later, and then twice-daily (morning and evening) for the next 2 days. The exact number of tablets depends on body weight — always follow your doctor’s or pharmacist’s instructions.
Do not use Coartem if you are allergic to artemether, lumefantrine, or any of the other ingredients. Avoid co-administration with strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, or St. John’s wort, as they can reduce effectiveness. Coartem should not be used in people with known QT prolongation, low potassium or magnesium levels, or those taking other drugs that prolong the QT interval. Do not take halofantrine within one month of using Coartem. Inform your doctor about all medicines you take, including herbal products.

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