Lopinavir Ritonavir – A Brand of Lopinavir + Ritonavir for HIV-1 Infection
Lopinavir Ritonavir is a brand of the combination medicine lopinavir + ritonavir. It is an HIV-1 protease inhibitor used with other antiretroviral medicines to treat HIV-1 infection in adults and children from 14 days old. Available as 200 mg / 50 mg tablets, it is registered with NAFDAC under number A4-1023. Drugstore.ng does not currently list this medicine.
- Generic: Lopinavir + Ritonavir
- Strength: 200 mg; 50 mg
- Form: Tablet
- NAFDAC No.: A4-1023
What it is
Lopinavir Ritonavir is a brand of lopinavir + ritonavir, a combination of two HIV-1 protease inhibitors. Protease inhibitors block an enzyme that the HIV virus needs to multiply, helping to control the infection.
What it's used for
Lopinavir + ritonavir is used together with other antiretroviral medicines to treat HIV-1 infection in adults and children aged 14 days and older. Before starting, doctors may use resistance testing to see if the virus is likely to respond to this treatment.
How it's taken
The tablets are taken by mouth. They may be taken with or without food, but should be swallowed whole – not chewed, broken, or crushed. The typical total daily dose is 800 mg of lopinavir and 200 mg of ritonavir, given once or twice a day. Your doctor will decide the right regimen for you. Do not change your dose without medical advice.
Common side effects
Common side effects include diarrhoea, nausea, vomiting, high triglycerides (a type of fat in the blood), and high cholesterol. If any side effect bothers you, speak with your doctor or pharmacist.
Important cautions
This medicine is not for anyone who has had a serious allergic reaction to lopinavir, ritonavir, or any ingredient. It can interact with many other drugs, especially those broken down by the liver enzyme CYP3A – these interactions may be dangerous. It may also cause pancreatitis, liver problems, or changes in heart rhythm (QT or PR interval prolongation). Lopinavir + ritonavir oral solution must not be used in preterm newborns soon after birth. Tell your doctor about all medicines you take.
Frequently asked questions
What is Lopinavir Ritonavir used for?
Lopinavir Ritonavir is used as part of a combination treatment for HIV-1 infection. It helps lower the amount of virus in the body and improve the immune system.
What are the side effects of Lopinavir Ritonavir?
Common side effects include diarrhoea, nausea, vomiting, and changes in blood fats (high triglycerides and high cholesterol). Serious but less common side effects include pancreatitis, liver damage, and heart rhythm changes.
Is Lopinavir Ritonavir available in Nigeria?
Lopinavir Ritonavir is registered with NAFDAC (registration number A4-1023) for use in Nigeria, but Drugstore.ng does not currently stock it. You can request it and we will ask partner pharmacies to source it.
What is the generic name of Lopinavir Ritonavir?
The generic name is lopinavir + ritonavir (a combination of two active ingredients).
How should I take Lopinavir Ritonavir tablets?
Swallow the tablets whole with or without food. Do not chew, crush, or break them. The usual dose is 800 mg lopinavir/200 mg ritonavir total per day, given once or twice daily as prescribed by your doctor.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.