Paclitaxel 300 mg/50 mL Concentrate For Solution For Infusion

Paclitaxel is a chemotherapy medicine used to treat advanced ovarian cancer and breast cancer. It is given as an intravenous infusion after premedication to reduce the risk of allergic reactions.

What it is

Paclitaxel is a chemotherapy drug used to treat certain cancers. It works by interfering with the growth of cancer cells.

What it's used for

This medicine is used for the treatment of advanced ovarian cancer, either as subsequent therapy or as first-line treatment in combination with cisplatin. It is also used as adjuvant therapy for node-positive breast cancer after standard chemotherapy with doxorubicin.

Common side effects

Serious side effects include severe allergic reactions (e.g., difficulty breathing, low blood pressure, swelling), low white blood cell counts (increasing infection risk), low red blood cell counts (anaemia), low platelet counts (bleeding risk), and nerve damage causing numbness or tingling. Your doctor will monitor your blood counts and manage these effects.

Important cautions

Paclitaxel should not be used if you have a history of severe allergic reactions to paclitaxel or any ingredient in the formulation (such as polyoxyl 35 castor oil). It is also contraindicated if your neutrophil count is below 1,500 cells/mm³ (for solid tumours) or below 1,000 cells/mm³ (for AIDS-related Kaposi's sarcoma). Allergic reactions can be life-threatening even with premedication. The infusion must be given using non-PVC equipment to reduce exposure to DEHP plasticiser.

Frequently asked questions

What is paclitaxel used for?

Paclitaxel is used to treat advanced ovarian cancer (alone or with cisplatin) and as adjuvant therapy for node-positive breast cancer.

How is paclitaxel taken?

It is given as an intravenous infusion (drip) into a vein, usually over several hours. Before each infusion, you will receive medicines to help prevent allergic reactions.

Can I buy paclitaxel without a prescription in Nigeria?

Based on our records, paclitaxel is classified as an over-the-counter medicine. However, because it is a strong chemotherapy drug, you should only use it under the supervision of a healthcare professional.

What are the serious side effects of paclitaxel?

Serious side effects include severe allergic reactions, low blood cell counts (leading to infections, anaemia, or bleeding), and nerve damage causing numbness or tingling in the hands or feet.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.