MabThera 1400 mg Solution for Subcutaneous Injection

MabThera is a brand of rituximab, a monoclonal antibody used to treat certain types of cancer, specifically Non-Hodgkin's Lymphoma.

What it is

Rituximab is a CD20-directed cytolytic antibody, which is a type of targeted therapy that helps the immune system destroy cancer cells. It is a monoclonal antibody.

What it's used for

MabThera is used to treat adult patients with Non-Hodgkin's Lymphoma (NHL). This includes relapsed or refractory low-grade or follicular CD20-positive B-cell NHL (used alone), previously untreated follicular CD20-positive B-cell NHL (used with chemotherapy and then alone as maintenance), and non-progressing low-grade CD20-positive B-cell NHL after first-line chemotherapy (used alone). It is also used for other indications as determined by a doctor.

Common side effects

Common side effects include infusion-related reactions (fever, chills, nausea), severe skin reactions, reactivation of hepatitis B virus, progressive multifocal leukoencephalopathy (a rare brain infection), tumor lysis syndrome (rapid breakdown of cancer cells), increased risk of infections, and heart-related problems. Seek medical attention if you experience any severe symptoms.

Important cautions

MabThera can cause serious side effects. Before treatment, your doctor will check for hepatitis B infection. During treatment, you will be monitored for infusion reactions, infections, heart problems, kidney problems, and bowel issues. If you experience abdominal pain, vomiting, or signs of infection, tell your doctor immediately. Do not receive live vaccines during treatment.

Frequently asked questions

What is MabThera used for?

MabThera is used to treat Non-Hodgkin's Lymphoma, a type of blood cancer. It may be used alone or in combination with chemotherapy.

What are the side effects of MabThera?

Side effects include infusion reactions, infections, skin reactions, reactivation of hepatitis B, and heart problems. A full list is available in the product information.

How is MabThera taken?

MabThera is given as an intravenous infusion (drip) by a doctor or nurse. It must be given in a hospital or clinic setting because serious allergic reactions can occur.

Can I buy MabThera without a prescription in Nigeria?

Yes, MabThera is available over the counter in Nigeria. However, because it is an injectable medicine that must be administered by a healthcare professional, you will need to arrange for administration at a suitable facility.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.