Mabthera 100 mg Concentrate for Solution for Infusion
Mabthera (Rituximab) 100mg solution is a medicine used in the treatment of certain types of cancer, specifically Non-Hodgkin's Lymphoma. It is a type of monoclonal antibody that targets CD20-positive cells.
What it is
Rituximab is a CD20-directed cytolytic antibody, meaning it targets and helps destroy certain immune cells that carry the CD20 protein on their surface. It is used in cancer therapy.
What it's used for
Rituximab is used for the treatment of adult patients with Non-Hodgkin's Lymphoma (NHL), including: relapsed or refractory low-grade or follicular CD20-positive B-cell NHL; previously untreated follicular CD20-positive B-cell NHL in combination with chemotherapy; and as maintenance therapy after response. It is also used for non-progressing low-grade CD20-positive B-cell NHL after certain chemotherapy regimens, and for previously untreated diffuse large B-cell lymphoma.
Common side effects
Common side effects include infusion-related reactions (such as fever, chills, and low blood pressure), severe mucocutaneous reactions, reactivation of hepatitis B infection, progressive multifocal leukoencephalopathy, tumour lysis syndrome, infections, and cardiovascular problems. Your healthcare provider will monitor you closely.
Important cautions
Important precautions include: monitoring for tumour lysis syndrome (with aggressive hydration and anti-uric acid medicines), watching for infections and stopping treatment if they occur, discontinuing the infusion if serious heart problems develop, monitoring kidney function, and being alert for bowel obstruction or perforation (pain, vomiting).
Frequently asked questions
What is Mabthera used for?
Mabthera (Rituximab) is used to treat types of Non-Hodgkin's Lymphoma, a cancer of the immune system. It works by targeting and destroying CD20-positive B-cells.
What are the side effects of Mabthera?
Common side effects include fever, chills, low blood pressure during infusion, infections, hepatitis B reactivation, tumour lysis syndrome, and heart problems. Your doctor will monitor for these.
Can I buy Mabthera without a prescription in Nigeria?
Mabthera is classified as an over-the-counter medicine. However, because it must be given as an intravenous infusion by a healthcare professional, you will need a doctor's supervision to receive it.
How is Mabthera taken?
Mabthera is given as an intravenous infusion (IV drip) in a hospital or clinic. It is not taken by mouth. The infusion is typically given over several hours.
This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.
