Glucovance 500 mg/2.5 mg Tablet (Metformin Hydrochloride; Glibenclamide)


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Glucovance is a combination tablet containing glibenclamide and metformin. It is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

What it is

Glucovance is a combination medicine. One of its active ingredients, glibenclamide, belongs to a class of drugs called sulfonylureas. Sulfonylureas help lower blood sugar by stimulating the pancreas to release more insulin.

What it's used for

This medicine is used together with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes mellitus.

Common side effects

Common side effects include low blood sugar (hypoglycemia), nausea, a feeling of fullness in the stomach, and heartburn. These are often dose-related and may go away when the dose is reduced.

Important cautions

Do not use this medicine if you have type 1 diabetes, diabetic ketoacidosis, or a known allergy to glibenclamide. It should not be taken with bosentan. There is a warning about an increased risk of cardiovascular death when using oral hypoglycemic medicines compared to diet alone. Tell your doctor about all other medicines you take.

Frequently asked questions

What is Glucovance used for?

Glucovance is used to help control blood sugar in adults with type 2 diabetes. It should be used along with diet and exercise.

Can I buy Glucovance without a prescription in Nigeria?

Yes, Glucovance is available over the counter in Nigeria. However, diabetes management requires close medical supervision. It is advisable to consult a doctor before starting any diabetes medicine.

What are the side effects of Glucovance?

Common side effects include low blood sugar (sweating, shaking, dizziness), nausea, stomach fullness, and heartburn. If you experience jaundice or signs of liver problems, stop the medicine and see a doctor.

How should I take Glucovance?

Take Glucovance by mouth with meals. The dose is determined by your doctor based on your blood sugar levels. Always follow your doctor's instructions and monitor your blood sugar regularly.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.

Glucovance is taken by mouth, typically once or twice daily with meals. The dose must be individualised. Your doctor will start with a low dose and adjust it based on your blood sugar levels. Do not change your dose without your doctor's advice.
Do not use this medicine if you have type 1 diabetes, diabetic ketoacidosis, or a known allergy to glibenclamide. It should not be taken with bosentan. There is a warning about an increased risk of cardiovascular death when using oral hypoglycemic medicines compared to diet alone. Tell your doctor about all other medicines you take.

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