Cycloserine Capsules USP 250 mg


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Cycloserine is an antibiotic used to treat tuberculosis when first-line medicines are not enough. It is taken by mouth and is available without a prescription in Nigeria, but medical supervision is strongly advised because of serious side effects.

What it is

Cycloserine is an antibiotic used to treat tuberculosis (a bacterial infection that usually affects the lungs). It is known as a second-line medicine, meaning it is used when standard tuberculosis drugs have not worked well.

What it's used for

Cycloserine is used for active tuberculosis of the lungs and other parts of the body (such as the kidneys) when the bacteria are sensitive to it. It must always be taken together with other tuberculosis medicines, never alone. It may also be used for some urinary tract infections caused by bacteria that are susceptible to it.

Common side effects

Common side effects affect the nervous system and may include: drowsiness, headache, tremor, slurred speech, dizziness, confusion, memory loss, and mood changes such as depression or psychosis (including suicidal thoughts). Seizures (convulsions) can also occur, especially with higher doses. Other reactions include skin rash and allergic reactions.

Important cautions

Do not take cycloserine if you have a history of epilepsy, severe depression, anxiety, psychosis, or if you have severe kidney disease. Also avoid it if you are allergic to cycloserine or if you drink excessive amounts of alcohol. If you develop any nervous system symptoms (such as confusion, drowsiness, headache, or seizures), stop the medicine and contact your doctor immediately – the dose may need to be lowered or treatment stopped. Blood levels above 30 mcg/mL increase the risk of toxicity, so blood tests are typically done.

Frequently asked questions

What is cycloserine used for?

Cycloserine is an antibiotic used to treat tuberculosis, usually when first-line TB medicines have not worked. It is also used for some urinary tract infections.

Can I buy cycloserine without a prescription in Nigeria?

Yes, cycloserine is available over-the-counter in Nigeria. However, because it can cause serious side effects, you should only take it under the supervision of a doctor.

What are the side effects of cycloserine?

Common side effects include drowsiness, headache, dizziness, confusion, memory problems, mood changes, and seizures. These are more likely with higher doses. Contact your doctor if you notice any of these.

How should cycloserine be taken?

Cycloserine is taken by mouth as a capsule. Adults typically start with 250 mg twice a day. Your doctor will adjust your dose based on your blood levels. Never take more than 1 gram per day.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.

Cycloserine is taken by mouth as a capsule. The usual starting dose for adults is 250 mg every 12 hours for the first 2 weeks. After that, the dose may be increased up to 1 gram per day, but not more. Your doctor will monitor your blood levels of the medicine to find the right dose. Always follow the exact instructions given by your healthcare provider.
Do not take cycloserine if you have a history of epilepsy, severe depression, anxiety, psychosis, or if you have severe kidney disease. Also avoid it if you are allergic to cycloserine or if you drink excessive amounts of alcohol. If you develop any nervous system symptoms (such as confusion, drowsiness, headache, or seizures), stop the medicine and contact your doctor immediately – the dose may need to be lowered or treatment stopped. Blood levels above 30 mcg/mL increase the risk of toxicity, so blood tests are typically done.

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