Amphotret Injection

Amphotret Injection 50 mg (Amphotericin B) – Uses, Dosage & Benefits Amphotret Injection contains amphotericin B, a broad-spectrum antifungal medication used for the treatment of severe systemic fungal infections. It is formulated as a lyophilized powder with sodium deoxycholate to enhance solubility and intravenous administration. This medicine is commonly used for: Treatment of systemic candidiasis Management of cryptococcal meningitis Treatment of aspergillosis Severe deep fungal infections in immunocompromised patients Fungal infections unresponsive to other antifungal therapies It works by binding to ergosterol in fungal cell membranes, creating pores that disrupt membrane integrity, leading to leakage of cellular contents and fungal cell death. Composition Each vial contains: Amphotericin B IP – 50 mg Sodium Deoxycholate (as solubiliser) – q.s. Sodium Phosphate (as buffer) – q.s. Excipients – q.s. Dosage and Administration Route of Administration: Intravenous Administered only under strict medical supervision in a hospital setting. The lyophilized powder must be reconstituted before intravenous infusion. Dosage is individualized based on infection severity, patient condition, and therapeutic response. Slow infusion is required to minimize adverse reactions. Key Benefits Effective against a wide range of systemic fungal infections Life-saving antifungal therapy in severe cases Suitable for hospital and intensive care use Well-established formulation for intravenous administration Important Information This is a Prescription-Only Medicine (POM). Must be administered only by trained healthcare professionals. May cause serious side effects such as fever, chills, infusion reactions, and kidney toxicity. Regular monitoring of renal function and electrolytes is required during treatment. Use only under strict medical supervision. Product Description Amphotret Injection 50 mg is a yellow-colored lyophilized powder for solution for injection supplied in a vial, intended for intravenous use after reconstitution in the treatment of severe systemic fungal infections.