Amatem Forte Soft Gel Capsules (Artemether; Lumefantrine 80 mg; 480 mg)


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Amatem is a combination antimalarial medicine used to treat acute, uncomplicated malaria caused by Plasmodium falciparum in adults and children 2 months and older weighing at least 5 kg.

What it is

Amatem is a combination antimalarial medicine containing artemether and lumefantrine. It belongs to a class of medicines called artemisinin‑based combination therapies (ACTs).

What it's used for

It is used to treat acute, uncomplicated malaria infections caused by Plasmodium falciparum. It is not approved for preventing malaria or for treating severe or complicated malaria.

Common side effects

The most common side effects in adults include headache, loss of appetite, dizziness, weakness, joint pain, and muscle pain. These are usually mild and go away on their own.

Important cautions

Do not use Amatem if you are allergic to artemether or lumefantrine. It should not be taken with strong CYP3A4 inducers (such as rifampin, carbamazepine, or St. John’s wort) as they may reduce its effectiveness. Avoid using Amatem with other medicines that prolong the QT interval, or if you have a prolonged QT interval, low potassium, or low magnesium. Amatem is not for severe or complicated malaria.

Frequently asked questions

What is Amatem used for?

Amatem is used to treat acute, uncomplicated malaria caused by the Plasmodium falciparum parasite. It is not used to prevent malaria.

How should I take Amatem?

Take Amatem with food. The standard course is 6 doses over 3 days: first dose, second dose after 8 hours, then twice daily for the next 2 days. Follow your healthcare provider’s advice exactly.

Can I buy Amatem without a prescription in Nigeria?

Yes, Amatem is available over the counter (OTC) in Nigeria. However, it is always advisable to use it under medical supervision.

What are the possible side effects of Amatem?

The most common side effects are headache, loss of appetite, dizziness, tiredness, joint pain, and muscle pain. Tell your doctor if any side effect bothers you.

Is Amatem safe for children?

Amatem can be used in children 2 months of age and older who weigh at least 5 kg. The dose depends on body weight, so a doctor or pharmacist should determine the right amount.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.

Amatem should be taken with food. It is typically given as a three‑day course of six doses: an initial dose, a second dose 8 hours later, then twice daily (morning and evening) for the next 2 days. Always follow your healthcare provider’s instructions.
Do not use Amatem if you are allergic to artemether or lumefantrine. It should not be taken with strong CYP3A4 inducers (such as rifampin, carbamazepine, or St. John’s wort) as they may reduce its effectiveness. Avoid using Amatem with other medicines that prolong the QT interval, or if you have a prolonged QT interval, low potassium, or low magnesium. Amatem is not for severe or complicated malaria.

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