Malarone 250mg, 100mg Tablet (12 Tablets) Atovaquone, Proguanil


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Malarone is a combination antimalarial tablet used to prevent and treat certain types of malaria. Each tablet contains 250 mg of atovaquone and 100 mg of proguanil hydrochloride. It is available over the counter in Nigeria.

What it is

Malarone is a combination antimalarial medicine. It contains two active ingredients: atovaquone and proguanil. Together, they work to prevent and treat infections caused by the Plasmodium falciparum parasite, which causes malaria.

What it's used for

This medicine is used for two main purposes: preventing malaria (prophylaxis) in adults and children when traveling to areas where malaria is common, including regions where chloroquine resistance has been reported; and treating acute, uncomplicated malaria caused by Plasmodium falciparum.

Common side effects

Common side effects in adults taking this medicine for prevention include diarrhoea, unusual dreams, mouth ulcers, and headache. In children, common side effects are abdominal pain, headache, cough, and vomiting. For treatment, common side effects include abdominal pain, nausea, vomiting, headache, diarrhoea, weakness, loss of appetite, and dizziness.

Important cautions

Do not use Malarone if you are allergic to atovaquone, proguanil, or any ingredient in the tablet. It should not be used to prevent malaria in people with severe kidney problems (creatinine clearance less than 30 mL/min). If you have diarrhoea or vomiting, the medicine may not be absorbed well – your doctor may monitor your condition closely. In mixed malaria infections, there is a risk of relapse of Plasmodium vivax after treatment. Tell your doctor about all other medicines you take.

Frequently asked questions

What is Malarone used for?

Malarone is used to prevent malaria (prophylaxis) in people traveling to areas where malaria is present, and to treat acute, uncomplicated malaria caused by the Plasmodium falciparum parasite.

How should I take Malarone?

Take one tablet daily at the same time, with food or a milky drink. If you vomit within one hour, take another tablet. For prevention, start 1–2 days before travel, continue during your stay, and for 7 days after leaving the malaria area. Always follow your doctor's instructions.

What are the side effects of Malarone?

Common side effects include diarrhoea, headache, nausea, abdominal pain, vomiting, unusual dreams, mouth ulcers, loss of appetite, and dizziness. Some side effects differ between prevention and treatment use. Tell your doctor if any side effect is severe or does not go away.

Can I buy Malarone without a prescription in Nigeria?

Yes, Malarone is available over the counter (OTC) in Nigeria. However, you should consult a doctor or pharmacist before use to ensure it is right for you, especially for children or if you have other health conditions.

Is Malarone safe for children?

Malarone is approved for use in children for both prevention and treatment of malaria. The dose depends on weight. Always give the correct dose as advised by a doctor or pharmacist. Common side effects in children include abdominal pain, headache, cough, and vomiting.

This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.

Take Malarone at the same time each day with food or a milky drink. If you vomit within one hour of taking the tablet, take another full dose. For those who have trouble swallowing, the tablet can be crushed and mixed with condensed milk just before taking. Typically, for prevention, you start taking it 1–2 days before entering a malaria area and continue during your stay and for 7 days after leaving. Always follow your doctor's instructions or the package leaflet. Talk to your pharmacist or doctor for the correct dosing schedule.
Do not use Malarone if you are allergic to atovaquone, proguanil, or any ingredient in the tablet. It should not be used to prevent malaria in people with severe kidney problems (creatinine clearance less than 30 mL/min). If you have diarrhoea or vomiting, the medicine may not be absorbed well – your doctor may monitor your condition closely. In mixed malaria infections, there is a risk of relapse of Plasmodium vivax after treatment. Tell your doctor about all other medicines you take.

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