AFLOTIN 20/120

Aflotin 60/360 Tablet is a combination antimalarial medication containing Artemether and Lumefantrine as active ingredients. This oral formulation is manufactured by Ajanta Pharma Limited in India and was marketed in Nigeria by Ajanta Pharma Nigeria Limited. Although Aflotin 60/360 Tablet is currently listed as inactive, it is important to understand its intended use, composition, and regulatory background.

Product Details

Active Ingredients

• Artemether: 60 mg per tablet
• Artemether is a fast-acting antimalarial agent derived from artemisinin, known for its rapid parasite clearance.
• Lumefantrine: 360 mg per tablet
• Lumefantrine is a long-acting antimalarial that complements artemether by preventing recurrence and relapse.

Dosage Form and Strength

• Form: Tablet
• Strength: 60 mg Artemether and 360 mg Lumefantrine per tablet

Route of Administration (ROA)

• Oral: Intended to be taken by mouth, usually with food to improve absorption.

Indications and Usage

Aflotin 60/360 Tablet was indicated for the treatment of uncomplicated malaria caused by Plasmodium falciparum, including cases where the parasite may be resistant to other antimalarial drugs. The combination of artemether and lumefantrine is recommended by the World Health Organization (WHO) as a first-line therapy for malaria in many regions.

Dosage and Administration

• Typical Dosage: The standard regimen involves several doses taken over a three-day period, but the dosage and duration should always be determined by a healthcare professional.
• Administration Advice: Tablets are best taken with food or a milk-based drink to enhance absorption, particularly of lumefantrine.

Regulatory and Product Information

• Manufacturer: Ajanta Pharma Limited, India
• Product Category: Drugs
• Marketing Category: Over-the-counter (OTC)

Safety Information

• Contraindications: Known hypersensitivity to artemether, lumefantrine, or any tablet component.
• Precautions: Use with caution in patients with a history of cardiac arrhythmias, electrolyte imbalance, or severe hepatic impairment.
• Possible Side Effects: Headache, dizziness, loss of appetite, gastrointestinal disturbances (nausea, vomiting, abdominal pain), and palpitations. Serious side effects are rare but require prompt medical attention.
• Drug Interactions: May interact with other antimalarials, certain antibiotics, and medications that affect cardiac rhythm.

Storage Conditions

• Store in a cool, dry place below 30°C.
• Protect from light and moisture.
• Keep out of reach of children.

Disclaimer

This article is intended for informational purposes only and does not replace professional medical advice. Please consult a healthcare provider for diagnosis and treatment of malaria or any other medical condition.